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Biosafety studies of carrier cells infected with a replication-competent adenovirus introduced by IAI.3B promoter
The use of carrier cells infected with oncolytic viruses in cancer gene therapy is an attractive method because it can overcome viral immunogenicity and induce tumor immunity and significant antitumor activity. To enable human clinical trials of this treatment, acute and chronic toxicity tests must...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362384/ https://www.ncbi.nlm.nih.gov/pubmed/26015963 http://dx.doi.org/10.1038/mtm.2014.19 |