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Genetic rearrangements of variable di-residue (RVD)-containing repeat arrays in a baculoviral TALEN system
Virus-derived gene transfer vectors have been successfully employed to express the transcription activator-like effector nucleases (TALENs) in mammalian cells. Since the DNA-binding domains of TALENs consist of the variable di-residue (RVD)-containing tandem repeat modules and virus genome with repe...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362386/ https://www.ncbi.nlm.nih.gov/pubmed/26015987 http://dx.doi.org/10.1038/mtm.2014.50 |