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TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1

AIM: TRPC3 is a non-selective cation channel, which forms a Ca(2+) entry pathway involved in cardiac remodelling. Our aim was to analyse acute electrophysiological and contractile consequences of TRPC3 activation in the heart. METHODS AND RESULTS: We used a murine model of cardiac TRPC3 overexpressi...

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Detalles Bibliográficos
Autores principales: Doleschal, Bernhard, Primessnig, Uwe, Wölkart, Gerald, Wolf, Stefan, Schernthaner, Michaela, Lichtenegger, Michaela, Glasnov, Toma N., Kappe, C. Oliver, Mayer, Bernd, Antoons, Gudrun, Heinzel, Frank, Poteser, Michael, Groschner, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362401/
https://www.ncbi.nlm.nih.gov/pubmed/25631581
http://dx.doi.org/10.1093/cvr/cvv022