NORE1A is a Ras senescence effector that controls the apoptotic/senescent balance of p53 via HIPK2

The Ras oncoprotein is a key driver of cancer. However, Ras also provokes senescence, which serves as a major barrier to Ras-driven transformation. Ras senescence pathways remain poorly characterized. NORE1A is a novel Ras effector that serves as a tumor suppressor. It is frequently inactivated in t...

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Detalles Bibliográficos
Autores principales: Donninger, Howard, Calvisi, Diego F., Barnoud, Thibaut, Clark, Jennifer, Schmidt, M. Lee, Vos, Michele D., Clark, Geoffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362463/
https://www.ncbi.nlm.nih.gov/pubmed/25778922
http://dx.doi.org/10.1083/jcb.201408087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362463/
https://www.ncbi.nlm.nih.gov/pubmed/25778922
http://dx.doi.org/10.1083/jcb.201408087

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