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Injury-stimulated Hedgehog signaling promotes regenerative proliferation of Drosophila intestinal stem cells

Many adult tissues are maintained by resident stem cells that elevate their proliferation in response to injury. The regulatory mechanisms underlying regenerative proliferation are still poorly understood. Here we show that injury induces Hedgehog (Hh) signaling in enteroblasts (EBs) to promote inte...

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Detalles Bibliográficos
Autores principales: Tian, Aiguo, Shi, Qing, Jiang, Alice, Li, Shuangxi, Wang, Bing, Jiang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362464/
https://www.ncbi.nlm.nih.gov/pubmed/25753035
http://dx.doi.org/10.1083/jcb.201409025