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Injury-stimulated Hedgehog signaling promotes regenerative proliferation of Drosophila intestinal stem cells
Many adult tissues are maintained by resident stem cells that elevate their proliferation in response to injury. The regulatory mechanisms underlying regenerative proliferation are still poorly understood. Here we show that injury induces Hedgehog (Hh) signaling in enteroblasts (EBs) to promote inte...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362464/ https://www.ncbi.nlm.nih.gov/pubmed/25753035 http://dx.doi.org/10.1083/jcb.201409025 |