Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth

Casein kinase 1δ/ε (CK1δ/ε) and their yeast homologue Hrr25 are essential for cell growth. Further, CK1δ is overexpressed in several malignancies, and CK1δ inhibitors have shown promise in several preclinical animal studies. However, the substrates of Hrr25 and CK1δ/ε that are necessary for cell gro...

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Detalles Bibliográficos
Autores principales: Ghalei, Homa, Schaub, Franz X., Doherty, Joanne R., Noguchi, Yoshihiko, Roush, William R., Cleveland, John L., Stroupe, M. Elizabeth, Karbstein, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362465/
https://www.ncbi.nlm.nih.gov/pubmed/25778921
http://dx.doi.org/10.1083/jcb.201409056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362465/
https://www.ncbi.nlm.nih.gov/pubmed/25778921
http://dx.doi.org/10.1083/jcb.201409056

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