Drosha Inclusions Are New Components of Dipeptide-Repeat Protein Aggregates in FTLD-TDP and ALS C9orf72 Expansion Cases

Frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are 2 neurodegenerative disorders that share clinical, genetic, and neuropathologic features. The presence of abnormal expansions of GGGGCC repeats (G4C2 repeats) in a noncoding region of the Chromosome 9 open reading f...

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Detalles Bibliográficos
Autores principales: Porta, Sílvia, Kwong, Linda K., Trojanowski, John Q., Lee, Virginia M.-Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neuropathologists 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362478/
https://www.ncbi.nlm.nih.gov/pubmed/25756586
http://dx.doi.org/10.1097/NEN.0000000000000182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362478/
https://www.ncbi.nlm.nih.gov/pubmed/25756586
http://dx.doi.org/10.1097/NEN.0000000000000182

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