EGFR-expression in primary urinary bladder cancer and corresponding metastases and the relation to HER2-expression. On the possibility to target these receptors with radionuclides

BACKGROUND: There is limited effect of tyrosine kinase inhibitors or “naked” antibodies binding EGFR or HER2 for therapy of metastasized urinary bladder cancer and these methods are therefore not routinely used. Targeting radio-nuclides to the extracellular domain of the receptors is potentially a b...

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Detalles Bibliográficos
Autores principales: Carlsson, Jörgen, Wester, Kenneth, De La Torre, Manuel, Malmström, Per-Uno, Gårdmark, Truls
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita, Warsaw 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362606/
https://www.ncbi.nlm.nih.gov/pubmed/25810701
http://dx.doi.org/10.2478/raon-2014-0015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362606/
https://www.ncbi.nlm.nih.gov/pubmed/25810701
http://dx.doi.org/10.2478/raon-2014-0015

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