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Improved corneal bioavailability of ofloxacin: biodegradable microsphere-loaded ion-activated in situ gel delivery system

The aim of the study was to improve corneal penetration and bioavailability of ofloxacin (OFX) eye preparations. OFX was incorporated in poly (lactide-co-glycolide) as biodegradable microspheres using oil in oil emulsion solvent evaporation technique. The prepared OFX microspheres were then incorpor...

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Detalles Bibliográficos
Autores principales: Sayed, Elshaimaa G, Hussein, Amal K, Khaled, Khaled A, Ahmed, Osama AA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362657/
https://www.ncbi.nlm.nih.gov/pubmed/25792803
http://dx.doi.org/10.2147/DDDT.S80697