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Dentate gyrus–CA3 glutamate release/NMDA transmission mediates behavioral despair and antidepressant-like responses to leptin

Compelling evidence supports the important role of the glutamatergic system in the pathophysiology of major depression and also as a target for rapid-acting antidepressants. However, the functional role of glutamate release/transmission in behavioral processes related to depression and antidepressan...

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Detalles Bibliográficos
Autores principales: Wang, Xuezhen, Zhang, Di, Lu, Xin-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362753/
https://www.ncbi.nlm.nih.gov/pubmed/25092243
http://dx.doi.org/10.1038/mp.2014.75