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The effects of sarcolipin over-expression in mouse skeletal muscle on metabolic activity

Studies in sarcolipin knockout mice have led to the suggestion that skeletal muscle sarcolipin plays a role in thermogenesis. The mechanism proposed is uncoupling of the sarcoplasmic reticulum calcium pump. However, in other work sarcolipin was not detected in mouse skeletal tissue. We have therefor...

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Detalles Bibliográficos
Autores principales: Butler, John, Smyth, Neil, Broadbridge, Robert, Council, Claire E., Lee, Anthony G., Stocker, Claire J., Hislop, David C., Arch, Jonathan R.S., Cawthorne, Michael A., Malcolm East, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362768/
https://www.ncbi.nlm.nih.gov/pubmed/25660043
http://dx.doi.org/10.1016/j.abb.2015.01.027