Activity-dependent degeneration of axotomized neuromuscular synapses in Wld(S) mice

Activity and disuse of synapses are thought to influence progression of several neurodegenerative diseases in which synaptic degeneration is an early sign. Here we tested whether stimulation or disuse renders neuromuscular synapses more or less vulnerable to degeneration, using axotomy as a robust t...

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Detalles Bibliográficos
Autores principales: Brown, R., Hynes-Allen, A., Swan, A.J., Dissanayake, K.N., Gillingwater, T.H., Ribchester, R.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362769/
https://www.ncbi.nlm.nih.gov/pubmed/25617654
http://dx.doi.org/10.1016/j.neuroscience.2015.01.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362769/
https://www.ncbi.nlm.nih.gov/pubmed/25617654
http://dx.doi.org/10.1016/j.neuroscience.2015.01.018

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