The Role of Poly(ADP-ribosyl)ation in DNA Damage Response and Cancer Chemotherapy

DNA damage is a deleterious threat, but occurs daily in all types of cells. In response to DNA damage, poly(ADP-ribosyl)ation, a unique posttranslational modification, is immediately catalyzed by poly(ADP-ribose) polymerases (PARPs) at DNA lesions, which facilitates DNA damage repair. Recent studies...

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Detalles Bibliográficos
Autores principales: Li, Mo, Yu, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362780/
https://www.ncbi.nlm.nih.gov/pubmed/25220415
http://dx.doi.org/10.1038/onc.2014.295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362780/
https://www.ncbi.nlm.nih.gov/pubmed/25220415
http://dx.doi.org/10.1038/onc.2014.295

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