The Serine Protease Inhibitor Elafin Maintains Normal Growth Control by Opposing the Mitogenic Effects of Neutrophil Elastase

The serine protease inhibitor, elafin, is a critical component of the epithelial barrier against neutrophil elastase (NE). Elafin is downregulated in the majority of breast cancer cell lines compared to normal human mammary epithelial cells (HMECs). Here, we evaluated the role of elafin and NE on pr...

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Detalles Bibliográficos
Autores principales: Caruso, Joseph A., Akli, Said, Pageon, Laura, Hunt, Kelly K., Keyomarsi, Khandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362782/
https://www.ncbi.nlm.nih.gov/pubmed/25195861
http://dx.doi.org/10.1038/onc.2014.284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362782/
https://www.ncbi.nlm.nih.gov/pubmed/25195861
http://dx.doi.org/10.1038/onc.2014.284

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