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Inhibition of NF-kappa B signaling restores responsiveness of castrate resistant prostate cancer cells to anti-androgen treatment by decreasing androgen receptor variants expression

Androgen receptor splicing variants (ARVs) which lack the ligand-binding domain (LBD) are associated with the development of castration-resistant prostate cancer (CRPC), including resistance to the new generation of high affinity anti-androgens. However, the mechanism by which ARVs expression is reg...

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Detalles Bibliográficos
Autores principales:	Jin, Renjie, Yamashita, Hironobu, Yu, Xiuping, Wang, Jingbin, Franco, Omar E., Wang, Yufen, Hayward, Simon W., Matusik, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362792/ https://www.ncbi.nlm.nih.gov/pubmed/25220414 http://dx.doi.org/10.1038/onc.2014.302

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