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Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis

OBJECTIVE: We aimed to investigate the effect of topical application of a Copper indomethacin (Cu-Indo) gel preparation on monosodium iodoacetate (MIA) induced arthritis of the knee joint of rats and to test our hypothesis that copper complex of indomethacin could be a more potent anti-inflammatory...

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Detalles Bibliográficos
Autores principales: Yassin, Nemat Z, El-Shenawy, Siham M, Abdel-Rahman, Rehab F, Yakoot, Mostafa, Hassan, Mohamed, Helmy, Sherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362896/
https://www.ncbi.nlm.nih.gov/pubmed/25792809
http://dx.doi.org/10.2147/DDDT.S79957