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Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis
OBJECTIVE: We aimed to investigate the effect of topical application of a Copper indomethacin (Cu-Indo) gel preparation on monosodium iodoacetate (MIA) induced arthritis of the knee joint of rats and to test our hypothesis that copper complex of indomethacin could be a more potent anti-inflammatory...
Autores principales: | Yassin, Nemat Z, El-Shenawy, Siham M, Abdel-Rahman, Rehab F, Yakoot, Mostafa, Hassan, Mohamed, Helmy, Sherine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362896/ https://www.ncbi.nlm.nih.gov/pubmed/25792809 http://dx.doi.org/10.2147/DDDT.S79957 |
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