Em08red, a dual functional antiproliferative emodin analogue, is a downregulator of ErbB2 expression and inducer of intracellular oxidative stress

Expression of ErbB2 protein is inversely correlated with the prognosis in cancer patients. Consequently, strategies targeting ErbB2 remain an attractive option in treating several types of malignancies, including oral cancer. In addition, many studies have shown that emodin and emodin derivatives ar...

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Detalles Bibliográficos
Autores principales: Liang, Fong-Pin, Lien, Jin-Cherng, Wu, Yu-Hua, Chen, Chien-Shu, Juang, Shin-Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362900/
https://www.ncbi.nlm.nih.gov/pubmed/25792810
http://dx.doi.org/10.2147/DDDT.S66647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362900/
https://www.ncbi.nlm.nih.gov/pubmed/25792810
http://dx.doi.org/10.2147/DDDT.S66647

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