Oxcarbazepine-loaded polymeric nanoparticles: development and permeability studies across in vitro models of the blood–brain barrier and human placental trophoblast

Encapsulation of antiepileptic drugs (AEDs) into nanoparticles may offer promise for treating pregnant women with epilepsy by improving brain delivery and limiting the transplacental permeability of AEDs to avoid fetal exposure and its consequent undesirable adverse effects. Oxcarbazepine-loaded nan...

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Detalles Bibliográficos
Autores principales: Lopalco, Antonio, Ali, Hazem, Denora, Nunzio, Rytting, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362902/
https://www.ncbi.nlm.nih.gov/pubmed/25792832
http://dx.doi.org/10.2147/IJN.S77498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362902/
https://www.ncbi.nlm.nih.gov/pubmed/25792832
http://dx.doi.org/10.2147/IJN.S77498

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