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Selective Mycobacterium tuberculosis Shikimate Kinase Inhibitors as Potential Antibacterials

Owing to the persistence of tuberculosis (TB) as well as the emergence of multidrug-resistant and extensively drug-resistant (XDR) forms of the disease, the development of new antitubercular drugs is crucial. Developing inhibitors of shikimate kinase (SK) in the shikimate pathway will provide a sele...

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Detalles Bibliográficos
Autores principales: Gordon, Sara, Simithy, Johayra, Goodwin, Douglas C, Calderón, Angela I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362912/
https://www.ncbi.nlm.nih.gov/pubmed/25861218
http://dx.doi.org/10.4137/PMC.S13212