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Evaluation of the live vaccine efficacy of virulence plasmid-cured, and phoP- or aroA-deficient Salmonella enterica serovar Typhimurium in mice

We evaluated the protective efficacy of 94-kb virulence plasmid-cured, and phoP- or aroA-deficient strains of Salmonella enterica serovar Typhimurium (ΔphoP or ΔaroA S. Typhimurium) as oral vaccine candidates in BALB/c mice. Two weeks after the completion of 3 oral immunizations with 1 × 10(8) colon...

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Detalles Bibliográficos
Autores principales: MATSUI, Hidenori, ISSHIKI, Yasunori, EGUCHI, Masahiro, OGAWA, Yohsuke, SHIMOJI, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363020/
https://www.ncbi.nlm.nih.gov/pubmed/25341392
http://dx.doi.org/10.1292/jvms.14-0013