IRF8 directs stress induced autophagy in macrophages and promotes clearance of Listeria monocytogenes

Autophagy, activated by many stresses, plays a critical role in innate immune responses. Here we show that Interferon Regulatory Factor 8 (IRF8) is required for expression of autophagy-related genes in dendritic cells. Furthermore in macrophages, IRF8 is induced by multiple autophagy-inducing stress...

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Detalles Bibliográficos
Autores principales: Gupta, Monica, Shin, Dong-Mi, Ramakrishna, Lakshmi, Goussetis, Dennis J., Platanias, Leonidas C., Xiong, Huabao, Morse, Herbert C., Ozato, Keiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363081/
https://www.ncbi.nlm.nih.gov/pubmed/25775030
http://dx.doi.org/10.1038/ncomms7379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363081/
https://www.ncbi.nlm.nih.gov/pubmed/25775030
http://dx.doi.org/10.1038/ncomms7379

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