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IRF8 directs stress induced autophagy in macrophages and promotes clearance of Listeria monocytogenes
Autophagy, activated by many stresses, plays a critical role in innate immune responses. Here we show that Interferon Regulatory Factor 8 (IRF8) is required for expression of autophagy-related genes in dendritic cells. Furthermore in macrophages, IRF8 is induced by multiple autophagy-inducing stress...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363081/ https://www.ncbi.nlm.nih.gov/pubmed/25775030 http://dx.doi.org/10.1038/ncomms7379 |