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Altered Pulmonary Artery Endothelial - Smooth Muscle Cell Interactions in Experimental Congenital Diaphragmatic Hernia

BACKGROUND: Pulmonary hypertension (PH) secondary to vascular remodeling contributes to poor outcomes in congenital diaphragmatic hernia (CDH), however mechanisms responsible are unknown. We hypothesized that pulmonary artery endothelial cell (PAEC) dysfunction contributes to smooth muscle cell (SMC...

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Detalles Bibliográficos
Autores principales: Acker, Shannon N., Seedorf, Gregory J., Abman, Steven H., Nozik-Grayck, Eva, Kuhn, Katherine, Partrick, David A., Gien, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363155/
https://www.ncbi.nlm.nih.gov/pubmed/25580737
http://dx.doi.org/10.1038/pr.2015.13