A simple data-adaptive probabilistic variant calling model

BACKGROUND: Several sources of noise obfuscate the identification of single nucleotide variation (SNV) in next generation sequencing data. For instance, errors may be introduced during library construction and sequencing steps. In addition, the reference genome and the algorithms used for the alignm...

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Detalles Bibliográficos
Autores principales: Hoffmann, Steve, Stadler, Peter F, Strimmer, Korbinian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363181/
https://www.ncbi.nlm.nih.gov/pubmed/25788974
http://dx.doi.org/10.1186/s13015-015-0037-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363181/
https://www.ncbi.nlm.nih.gov/pubmed/25788974
http://dx.doi.org/10.1186/s13015-015-0037-5

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