Cargando…
A simple data-adaptive probabilistic variant calling model
BACKGROUND: Several sources of noise obfuscate the identification of single nucleotide variation (SNV) in next generation sequencing data. For instance, errors may be introduced during library construction and sequencing steps. In addition, the reference genome and the algorithms used for the alignm...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363181/ https://www.ncbi.nlm.nih.gov/pubmed/25788974 http://dx.doi.org/10.1186/s13015-015-0037-5 |