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Activation of complement system in kidney after ketoprofen-induced kidney injury in sheep

BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat inflammatory pain in humans and animals. An overdose of an NSAID is nephrotoxic and can lead to acute kidney injury (AKI). Complement activation occurs in several types of renal disorders with proteinuria. The aim of...

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Detalles Bibliográficos
Autores principales: Palviainen, Mari J, Junnikkala, Sami, Raekallio, Marja, Meri, Seppo, Vainio, Outi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363187/
https://www.ncbi.nlm.nih.gov/pubmed/25887232
http://dx.doi.org/10.1186/s13028-015-0106-2