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Evaluation of High-Dose Daptomycin Versus Vancomycin Alone or Combined with Clarithromycin or Rifampin Against Staphylococcus aureus and S. epidermidis in a Novel In Vitro PK/PD Model of Bacterial Biofilm

INTRODUCTION: Medical device infections are associated with significant morbidity and mortality. These difficult-to-treat infections often result in antibiotic failure and resistance. Combination therapy is often required, however, the most optimal combination is unknown. We evaluated the in vitro a...

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Detalles Bibliográficos
Autores principales: Hall Snyder, Ashley D., Vidaillac, Celine, Rose, Warren, McRoberts, John P., Rybak, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363216/
https://www.ncbi.nlm.nih.gov/pubmed/25519162
http://dx.doi.org/10.1007/s40121-014-0055-5