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Evaluation of High-Dose Daptomycin Versus Vancomycin Alone or Combined with Clarithromycin or Rifampin Against Staphylococcus aureus and S. epidermidis in a Novel In Vitro PK/PD Model of Bacterial Biofilm
INTRODUCTION: Medical device infections are associated with significant morbidity and mortality. These difficult-to-treat infections often result in antibiotic failure and resistance. Combination therapy is often required, however, the most optimal combination is unknown. We evaluated the in vitro a...
Autores principales: | Hall Snyder, Ashley D., Vidaillac, Celine, Rose, Warren, McRoberts, John P., Rybak, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363216/ https://www.ncbi.nlm.nih.gov/pubmed/25519162 http://dx.doi.org/10.1007/s40121-014-0055-5 |
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