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Different Associations of CD45 Isoforms with STAT3, PKC and ERK Regulate IL-6-Induced Proliferation in Myeloma

In response to interleukin 6 (IL-6) stimulation, both CD45RO and CD45RB, but not CD45RA, translocate to lipid rafts. However, the significance of this distinct translocation and the downstream signals in CD45 isoforms-participated IL-6 signal are not well understood. Using sucrose fractionation, we...

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Detalles Bibliográficos
Autores principales: Zheng, Xu, Li, Allison S., Zheng, Huanyu, Zhao, Dongmei, Guan, Dagang, Zou, Huawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363322/
https://www.ncbi.nlm.nih.gov/pubmed/25781885
http://dx.doi.org/10.1371/journal.pone.0119780