Prion-like Mechanism in Amyotrophic Lateral Sclerosis: are Protein Aggregates the Key?

ALS is a fatal adult-onset motor neuron disease. Motor neurons in the cortex, brain stem and spinal cord gradually degenerate in ALS patients, and most ALS patients die within 3~5 years of disease onset due to respiratory failure. The major pathological hallmark of ALS is abnormal accumulation of pr...

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Detalles Bibliográficos
Autores principales: Lee, Shynrye, Kim, Hyung-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363329/
https://www.ncbi.nlm.nih.gov/pubmed/25792864
http://dx.doi.org/10.5607/en.2015.24.1.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363329/
https://www.ncbi.nlm.nih.gov/pubmed/25792864
http://dx.doi.org/10.5607/en.2015.24.1.1

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