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The effect of chemotherapeutic agents on tumor vasculature in subcutaneous and orthotopic human tumor xenografts

BACKGROUND: The growth of solid tumors and their regrowth after treatment is dependent upon functional tumor vasculature. Some chemotherapeutic agents have shown anti-angiogenic properties but there are limited studies of the effect of chemotherapy on tumor vasculature. Here we investigate the effec...

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Detalles Bibliográficos
Autores principales: Fung, Andrea S, Lee, Carol, Yu, Man, Tannock, Ian F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363401/
https://www.ncbi.nlm.nih.gov/pubmed/25884767
http://dx.doi.org/10.1186/s12885-015-1091-6