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CD4(+) T Cell Hyporesponsiveness after Repeated Exposure to Schistosoma mansoni Larvae Is Dependent upon Interleukin-10

The effect that multiple percutaneous exposures to Schistosoma larvae has on the development of early CD4(+) lymphocyte reactivity is unclear, yet it is important in the context of humans living in areas where schistosomiasis is endemic. In a murine model of multiple infections, we show that exposur...

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Detalles Bibliográficos
Autores principales: Prendergast, Catriona T., Sanin, David E., Cook, Peter C., Mountford, Adrian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363412/
https://www.ncbi.nlm.nih.gov/pubmed/25624353
http://dx.doi.org/10.1128/IAI.02831-14