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Cryptococcal Phospholipase B1 Is Required for Intracellular Proliferation and Control of Titan Cell Morphology during Macrophage Infection

Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of fungal-infection-related fatalities, especially in immunocompromised hosts. Several virulence factors are known to play a major role in the pathogenesis of cryptococcal infections, including the enzyme phospholipase B...

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Detalles Bibliográficos
Autores principales: Evans, Robert J., Li, Zhongming, Hughes, William S., Djordjevic, Julianne T., Nielsen, Kirsten, May, Robin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363446/
https://www.ncbi.nlm.nih.gov/pubmed/25605772
http://dx.doi.org/10.1128/IAI.03104-14