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Fmrp targets or not: long, highly brain-expressed genes tend to be implicated in autism and brain disorders

BACKGROUND: Many studies have demonstrated a robust statistical overlap between genes whose transcripts are reported as Fragile X Mental Retardation Protein (Fmrp)-binding targets and genes implicated in various psychiatric disorders, including autism. However, it is not clear how to interpret this...

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Detalles Bibliográficos
Autores principales: Ouwenga, Rebecca L, Dougherty, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363463/
https://www.ncbi.nlm.nih.gov/pubmed/25789151
http://dx.doi.org/10.1186/s13229-015-0008-1