Evaluating LRRK2 Genetic Variants with Unclear Pathogenicity

Mutations in the leucine-rich repeat kinase 2 (LRRK2) have been known to be a major genetic component affecting Parkinson's disease (PD). However, the pathogenicity of many of the LRRK2 variants is unclear because they have been detected in single patients or also in patients and controls. Here...

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Detalles Bibliográficos
Autores principales: Refai, Fathima Shaffra, Ng, Shin Hui, Tan, Eng-King
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363499/
https://www.ncbi.nlm.nih.gov/pubmed/25821816
http://dx.doi.org/10.1155/2015/678701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363499/
https://www.ncbi.nlm.nih.gov/pubmed/25821816
http://dx.doi.org/10.1155/2015/678701

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