The Transcription Factor C-Myc Suppresses MiR-23b and MiR-27b Transcription during Fetal Distress and Increases the Sensitivity of Neurons to Hypoxia-Induced Apoptosis

Previous studies reported that the expression of miR-23b-27b cluster was downregulated in embryonic brain cortices during hypoxia-induced neuronal apoptosis. However, the mechanism underlying this downregulation is not completely understood. Here, we report that the transcription factor c-Myc plays...

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Detalles Bibliográficos
Autores principales: Chen, Qun, Zhang, Fan, Wang, Yanbo, Liu, Zhengya, Sun, Anyang, Zen, Ke, Zhang, Chen-yu, Zhang, Qipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363589/
https://www.ncbi.nlm.nih.gov/pubmed/25781629
http://dx.doi.org/10.1371/journal.pone.0120217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363589/
https://www.ncbi.nlm.nih.gov/pubmed/25781629
http://dx.doi.org/10.1371/journal.pone.0120217

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