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Mitofusin 2-Deficiency Suppresses Cell Proliferation through Disturbance of Autophagy

Mitofusin2 (Mfn2), a mitochondrial outer membrane protein serving primarily as a mitochondrial fusion protein, has multiple functions in regulating cell biological processes. Defects of Mfn2 were found in diabetes, obesity, and neurodegenerative diseases. In the present study, we found that knockdow...

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Detalles Bibliográficos
Autores principales: Ding, Yanhong, Gao, Han, Zhao, Lifang, Wang, Xian, Zheng, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363693/
https://www.ncbi.nlm.nih.gov/pubmed/25781899
http://dx.doi.org/10.1371/journal.pone.0121328