Epigenetic Modulation with HDAC Inhibitor CG200745 Induces Anti-Proliferation in Non-Small Cell Lung Cancer Cells

Histone modification plays a pivotal role on gene regulation, as regarded as global epigenetic markers, especially in tumor related genes. Hence, chemical approaches targeting histone-modifying enzymes have emerged onto the main stage of anticancer drug discovery. Here, we investigated the therapeut...

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Detalles Bibliográficos
Autores principales: Chun, Sung-Min, Lee, Ji-Young, Choi, Jene, Lee, Je-Hwan, Hwang, Jung Jin, Kim, Chung-Soo, Suh, Young-Ah, Jang, Se Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363698/
https://www.ncbi.nlm.nih.gov/pubmed/25781604
http://dx.doi.org/10.1371/journal.pone.0119379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363698/
https://www.ncbi.nlm.nih.gov/pubmed/25781604
http://dx.doi.org/10.1371/journal.pone.0119379

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