Claudin-2 Knockout by TALEN-Mediated Gene Targeting in MDCK Cells: Claudin-2 Independently Determines the Leaky Property of Tight Junctions in MDCK Cells

Tight junctions (TJs) regulate the movements of substances through the paracellular pathway, and claudins are major determinants of TJ permeability. Claudin-2 forms high conductive cation pores in TJs. The suppression of claudin-2 expression by RNA interference in Madin-Darby canine kidney (MDCK) II...

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Detalles Bibliográficos
Autores principales: Tokuda, Shinsaku, Furuse, Mikio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363821/
https://www.ncbi.nlm.nih.gov/pubmed/25781928
http://dx.doi.org/10.1371/journal.pone.0119869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363821/
https://www.ncbi.nlm.nih.gov/pubmed/25781928
http://dx.doi.org/10.1371/journal.pone.0119869

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