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Inositol Depletion Restores Vesicle Transport in Yeast Phospholipid Flippase Mutants
In eukaryotic cells, type 4 P-type ATPases function as phospholipid flippases, which translocate phospholipids from the exoplasmic leaflet to the cytoplasmic leaflet of the lipid bilayer. Flippases function in the formation of transport vesicles, but the mechanism remains unknown. Here, we isolate a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363822/ https://www.ncbi.nlm.nih.gov/pubmed/25781026 http://dx.doi.org/10.1371/journal.pone.0120108 |