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Designed angiopoietin-1 variant, COMP-angiopoietin-1, rescues erectile function through healthy cavernous angiogenesis in a hypercholesterolemic mouse

Despite the advent of oral phosphodiesterase-5 inhibitors, curative treatment for erectile dysfunction (ED) remains unavailable. Recently, the link between ED and cardiovascular disease was unveiled and the main etiology of ED was found to be vasculogenic. Therefore, neovascularization is a promisin...

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Detalles Bibliográficos
Autores principales: Ryu, Ji-Kan, Kim, Woo Jean, Koh, Young Jun, Piao, Shuguang, Jin, Hai-Rong, Lee, Sae-Won, Choi, Min Ji, Shin, Hwa-Yean, Kwon, Mi-Hye, Jung, Keehoon, Koh, Gou Young, Suh, Jun-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363832/
https://www.ncbi.nlm.nih.gov/pubmed/25783805
http://dx.doi.org/10.1038/srep09222