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Sensitization of Gram-negative bacteria to rifampin and OAK combinations

While individually inefficient against Gram-negative bacteria, in-vitro combinations of rifampin and OAK were mutually synergistic since sub-minimal inhibitory concentrations of one compound have potentiated the other by 2–4 orders of magnitude. Synergy persisted in-vivo as single-dose systemic trea...

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Detalles Bibliográficos
Autores principales: Jammal, Joanna, Zaknoon, Fadia, Kaneti, Galoz, Goldberg, Keren, Mor, Amram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363860/
https://www.ncbi.nlm.nih.gov/pubmed/25782773
http://dx.doi.org/10.1038/srep09216