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Breeding scheme and maternal small RNAs affect the efficiency of transgenerational inheritance of a paramutation in mice
Paramutations result from interactions between two alleles at a single locus, whereby one induces a heritable change in the other. Although common in plants, paramutations are rarely studied in animals. Here, we report a new paramutation mouse model, in which the paramutant allele was induced by an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363887/ https://www.ncbi.nlm.nih.gov/pubmed/25783852 http://dx.doi.org/10.1038/srep09266 |