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Breeding scheme and maternal small RNAs affect the efficiency of transgenerational inheritance of a paramutation in mice

Paramutations result from interactions between two alleles at a single locus, whereby one induces a heritable change in the other. Although common in plants, paramutations are rarely studied in animals. Here, we report a new paramutation mouse model, in which the paramutant allele was induced by an...

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Detalles Bibliográficos
Autores principales: Yuan, Shuiqiao, Oliver, Daniel, Schuster, Andrew, Zheng, Huili, Yan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363887/
https://www.ncbi.nlm.nih.gov/pubmed/25783852
http://dx.doi.org/10.1038/srep09266