Cargando…
Differentially methylated CpG island within human XIST mediates alternative P2 transcription and YY1 binding
BACKGROUND: X-chromosome inactivation silences one X chromosome in females to achieve dosage compensation with the single X chromosome in males. While most genes are silenced on the inactive X chromosome, the gene for the long non-coding RNA XIST is silenced on the active X chromosome and expressed...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363909/ https://www.ncbi.nlm.nih.gov/pubmed/25200388 http://dx.doi.org/10.1186/s12863-014-0089-4 |