Differentially methylated CpG island within human XIST mediates alternative P2 transcription and YY1 binding

BACKGROUND: X-chromosome inactivation silences one X chromosome in females to achieve dosage compensation with the single X chromosome in males. While most genes are silenced on the inactive X chromosome, the gene for the long non-coding RNA XIST is silenced on the active X chromosome and expressed...

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Detalles Bibliográficos
Autores principales: Chapman, Andrew G, Cotton, Allison M, Kelsey, Angela D, Brown, Carolyn J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363909/
https://www.ncbi.nlm.nih.gov/pubmed/25200388
http://dx.doi.org/10.1186/s12863-014-0089-4

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