Alteration in methylation level at 11β-hydroxysteroid dehydrogenase type 2 gene promoter in infants born to preeclamptic women

BACKGROUND: Preeclampsia reduces placental expression and activity of 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2), leading to an increase in fetal glucocordicoids. The latter has been proposed to be associated with low birth weight and high risk of metabolic diseases in later life of the offsp...

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Detalles Bibliográficos
Autores principales: Hu, Wensheng, Weng, Xiaoling, Dong, Minyue, Liu, Yun, Li, Wenjuan, Huang, Hefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363912/
https://www.ncbi.nlm.nih.gov/pubmed/25200528
http://dx.doi.org/10.1186/s12863-014-0096-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363912/
https://www.ncbi.nlm.nih.gov/pubmed/25200528
http://dx.doi.org/10.1186/s12863-014-0096-5

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