IFNγ inhibits Th17 differentiation and function via Tbet-dependent and Tbet-independent mechanisms

The transcription factor Tbet is critical for the differentiation of Th1 CD4 T cells and is associated with the induction of multiple autoimmune diseases, including experimental autoimmune encephalomyelitis (EAE). Herein, we demonstrate that Tbet suppresses IL-17A and Th17 differentiation both in vi...

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Detalles Bibliográficos
Autores principales: Yeh, Wen-I, McWilliams, Ian L., Harrington, Laurie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363997/
https://www.ncbi.nlm.nih.gov/pubmed/24369297
http://dx.doi.org/10.1016/j.jneuroim.2013.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363997/
https://www.ncbi.nlm.nih.gov/pubmed/24369297
http://dx.doi.org/10.1016/j.jneuroim.2013.12.001

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