Lymphotoxin beta receptor signaling limits mucosal damage through driving IL-23 production by epithelial cells

The immune mechanisms regulating epithelial cell repair after injury remain poorly defined. We demonstrate here that lymphotoxin beta receptor (LTβR) signaling in intestinal epithelial cells promotes self-repair after mucosal damage. Using a conditional gene-targeted approach, we demonstrate that LT...

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Detalles Bibliográficos
Autores principales: Macho-Fernandez, Elise, Koroleva, Ekaterina P., Spencer, Cody M., Tighe, Michael, Torrado, Egidio, Cooper, Andrea M., Fu, Yang-Xin, Tumanov, Alexei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364000/
https://www.ncbi.nlm.nih.gov/pubmed/25183367
http://dx.doi.org/10.1038/mi.2014.78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364000/
https://www.ncbi.nlm.nih.gov/pubmed/25183367
http://dx.doi.org/10.1038/mi.2014.78

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