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A CRE/AP-1-Like Motif Is Essential for Induced Syncytin-2 Expression and Fusion in Human Trophoblast-Like Model

Syncytin-2 is encoded by the envelope gene of Endogenous Retrovirus-FRD (ERVFRD-1) and plays a critical role in fusion of placental trophoblasts leading to the formation of the multinucleated syncytiotrophoblast. Its expression is consequently regulated in a strict manner. In the present study, we h...

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Detalles Bibliográficos
Autores principales: Toufaily, Chirine, Lokossou, Adjimon Gatien, Vargas, Amandine, Rassart, Éric, Barbeau, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364025/
https://www.ncbi.nlm.nih.gov/pubmed/25781974
http://dx.doi.org/10.1371/journal.pone.0121468